Mouse Vestibular Ocular Reflex Testing System

GBR-Gait
Adjustable speed, Customized length and width, Enclosed camera

 

 

1. Precise Measurement of Inner Ear Components

The Mouse Vestibular Ocular Reflex Testing System is specifically designed to accurately measure the function of the semicircular canal and the utricle in mice. By leveraging the vestibulo-eye reflex, it offers a comprehensive assessment of the health of different parts of the vestibular organ, including both the semicircular canals and the otoliths. This level of precision is crucial for in-depth understanding of the inner ear's complex mechanisms and any associated disorders.

 

2. Application in Hair Cell Research

Given that the receptors of both the vestibular and auditory systems are hair cells, our VOR system extends its utility to research areas such as hair cell regeneration and auditory gene therapy. It provides researchers with a valuable tool to explore the potential of restoring or enhancing hair cell function, which could have far-reaching implications for treating hearing and balance disorders.

 

 

1. High Accuracy and Precision

When it comes to measuring eye movements, the Mouse Vestibular Ocular Reflex Testing System stands out with its exceptional accuracy and precision. This ensures that the data obtained is highly reliable, enabling researchers to make informed decisions and draw accurate conclusions about the vestibular functions being studied.

 

2. Efficient Testing Procedures

The testing procedures of our system are quick and efficient, saving valuable time and resources in the research process. This allows for a higher throughput of experiments, facilitating faster progress in understanding vestibular disorders and exploring potential treatments.

 

3. Broad Range of Vestibular Function Assessment

It has the ability to evaluate a wide spectrum of vestibular functions that are essential for maintaining balance and spatial orientation. This comprehensive assessment capability provides a more holistic view of the vestibular system, which is vital for uncovering the underlying mechanisms of various vestibular-related conditions.

 

4. Cost-Effective and Non-Invasive

Our Mouse Vestibular Ocular Reflex Testing System is not only highly accurate and efficient but also cost-effective and non-invasive. This makes it an ideal choice for both research institutions with budget constraints and clinical settings where patient comfort and accessibility are of utmost importance. It offers a practical and accessible solution for a wide range of applications without compromising on quality or performance.

 

 

The Mouse Vestibular Ocular Reflex Testing System finds extensive use in multiple key areas:

 

1. Vestibular Function Drug Screening

Facilitates the identification and evaluation of potential drugs that can target and improve vestibular function. By providing accurate and detailed data on the effects of different compounds on the vestibular system, it accelerates the drug discovery process and helps in the development of more effective treatments for vestibular disorders.

 

2. Vestibular Drug Toxicity Test

Enables the assessment of the potential toxicity of drugs on the vestibular system. This is crucial for ensuring the safety of new medications and preventing any adverse effects on the inner ear and balance function, thereby safeguarding patient health.

 

3. Semicircular Canal Function Study

Allows in-depth exploration of the specific functions and dysfunctions of the semicircular canals. This research is essential for understanding the role of these structures in balance control and for developing targeted interventions for disorders related to semicircular canal impairment.

 

4. Utricle Function Study

Similarly, it provides a platform for detailed investigation of the utricle's function and its contribution to overall vestibular function and balance. Insights gained from such studies can lead to improved diagnostic and treatment strategies for utricle-related conditions.

 

5. Inner Ear Morphology Differentiation and Hair Cell Regeneration Research

Aids in understanding the complex processes of inner ear morphology differentiation and the regeneration of hair cells. This knowledge is fundamental for developing novel therapies to address hearing loss and balance problems caused by hair cell damage or degeneration.

 

6. Hereditary Inner Ear Disease Treatment Research

Plays a significant role in studying hereditary inner ear diseases. By providing a means to assess the vestibular and auditory functions in mouse models of these diseases, it helps in the search for potential cures and the development of personalized treatment approaches.

 

 

GBR-MOVR Technical parameters
Platform performance parameters	Rotation angle accuracy: 0.2
	Screen: Tilt the touchscreen
VOR Test Parameters (Semicircular Canal Function)	Oscillating rotation mode: sinusoidal type, a total of 32 gears
	Swing frequency: 0.1-5Hz, a total of eight levels adjustable
	Swing angular velocity: The maximum angular velocity can be adjusted from 5-40*/s in four gears
OVAR mode (otolith function)	Tilt angle: 17°30° two modes
	Continuous rotation speed: four adjustable gears
Patented anesthesia-free fixation system analysis software	Low-contrast pupil recognition
	Eye tracking and pupil tracking combined
	Eye Movement Gain and Phase Analysis Software System
	Fast and slow phases are analyzed independently
	Skull 3D scan design
	Magnetic fixation, convenient and fast
	Fix 10-40 g body weight mice
Analysis software	Low-contrast pupil recognition
	Eye tracking and pupil tracking combined
	Eye Movement Gain and Phase Analysis Software System
	Fast and slow phases are analyzed independently

 

 

Precise Motor Behavior Analysis System

The vestibular system is the main peripheral sensory organ of the balance system. For research related to vestibular functions, we have a Mouse Vestibular Ocular Reflex Testing System that can detect the functions of the semicircular canals and the utricle in mice. It can assess the health status of different parts of the vestibular organ (semicircular canals and otoliths) through the vestibulo-ocular reflex and can be applied to research such as hair cell regeneration and auditory gene therapy. At the same time, we also have a Zebrafish Vestibular Ocular Reflex Testing System, which can evaluate the vestibular function of zebrafish larvae by detecting their utricle and saccule.

Meanwhile, we also possess behavior analysis systems for other species like locusts, cockroaches, police dogs, fruit flies, etc. These systems can adapt to diverse research directions and acquire precise behavioral data for analysis. Our behavior analysis systems feature high throughput, multi-angle, comprehensiveness, and diversity, contributing to every scientific research project.

 

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